The CRKL Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CRKL. This antibody recognizes Human antigen. The CRKL Antibody has been validated for the following applications: ELISA, Flow Cytometry, and Western Blot.
Description
Background: This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic